The 30th plenary meeting of the North South Ministerial Council, a body set up after the Good Friday Agreement, will take place at Farmleigh House.
It brings together ministers from the Government of Ireland and the Northern Ireland Executive twice a year.
The Northern Ireland Executive delegation will be led by First Minister Michelle O’Neill and deputy First Minister Emma Little-Pengelly.
The Dublin delegation will be led by Taoiseach Micheal Martin, who said it was an opportunity to discuss areas of “shared focus and ambition”.
Ministers also attended a shared dinner on Thursday evening.
Mr Martin said the plenary session will be the first opportunity for a collective cross-government and cross-border discussion on emergency planning and preparedness.
He said: “Weather events and