LOUISVILLE, Ky. —

At least nine people are dead and 16 others are unaccounted for after a UPS cargo plane caught fire and crashed Tuesday while taking off from the company's distribution hub in Louisville.

The McDonnell Douglas MD-11 went down around 5:15 p.m. Tuesday as it was taking off from Louisville Muhammad Ali International Airport, heading toward Daniel K. Inouye International Airport in Honolulu, Hawaii.

ABOVE VIDEO | Surveillance video shows fiery explosion as UPS plane rips through Louisville businesses

It was fully loaded with fuel for the long flight.

Video shows flames on the plane's left wing and a trail of smoke as it lifted briefly off the ground before skidding off the runway.

The plane crashed in a massive fireball, with fire and debris quickly spreading over

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