Former Pac-12 rivals will stage their first Big Ten matchup on Saturday as the No. 6 Oregon Ducks host the No. 16 USC Trojans . Oregon (9-1, 6-1 Big Ten) is riding a four-game win streak since suffering its lone loss of the year to Indiana, and the Ducks most recently defeated Minnesota, 42-13, last Friday. USC (8-2, 6-1 Big Ten) has won three in a row and knocked off Iowa, 26-21, in Week 12. USC leads the all-time series, 39-23-2.

Kickoff from Autzen Stadium in Eugene, Ore., is at 3:30 p.m. ET on CBS and Paramount+ . Oregon has won the last three matchups, with the most recent meeting coming in 2023. The Ducks are 10.5-point favorites in the latest Oregon vs. USC odds, while the over/under for total points scored is 59.5. Before making any USC vs. Oregon picks, check out the col

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