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It’s Day 2 of the ASH meeting. Let’s get straight into the news.

Fulcrum study suggests improved efficacy for higher dose sickle cell pill

Fulcrum Therapeutics said Sunday that a higher dose of its experimental pill for sickle cell disease was more effective at inducing an alternative form of the oxygen-carrying molecule hemoglobin — boosting hopes it could one day provide a simple and effective treatment for the disease.

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